Abul Bashar Ripon Khalipha1, 2*
1Department of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100,
2Evergreen Scientific Research Centre, Gopalganj-8100, Bangladesh

Cancer is one of the leading causes of death around the world, and if it is not detected in
time, it can quickly become terminal and incurable. Chemotherapy is a form of treatment
that can be used to get rid of, reduce the size of, or stop the progression of tumors. There
are many different formulations of chemotherapeutic medications from which to choose.
Some cancers can be treated effectively with a single class of chemotherapy medication,
while others may call for a multi-pronged approach that includes surgery, radiation,
and/or chemotherapy. The length of time spent receiving treatment might range anywhere
from a few minutes to many hours to several days. Every drug comes with the possibility
of causing potential side effects in some patients. Recent years have seen a surge in
interest among researchers in the therapeutic application of naturally occurring bioactive
chemicals in the fight against cancer. Some phytochemicals have effects on the
procedures and signaling pathways within cells, which may indicate that they can inhibit
tumor growth. In both in vivo and in vitro studies, phytochemicals were found to have
cancer-fighting properties that were beneficial. It is possible that the anticancer efficacy
of natural bioactive chemicals can be improved by encapsulating them in various drug
delivery systems. The efficiency of bioactive chemicals can be improved by making them
more stable and bioavailable in vivo, as well as by lowering the number of unintended
side effects and raising the level of activity that is specific to the target. The topic of
discussion in this article is a unique medication delivery system that can enclose naturally
occurring bioactive chemicals. In addition to this, it offers some insight into the
bioavailability of phytochemicals, as well as the difficulties and constraints of
conventional cancer treatment. In addition to that, it includes more current patents on
nanoparticle formulations that include a natural anti-cancer chemical.
Keywords: cancer, chemotherapy, drug delivery system, natural
bioactive compound, phytochemical, nanomedicine